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Document type:
journal article 
Author(s):
Wegener, Jörg W; Loga, Florian; Stegner, David; Nieswandt, Bernhard; Hofmann, Franz 
Title:
Phospholipase D1 is involved in ?1-adrenergic contraction of murine vascular smooth muscle. 
Abstract:
?1-Adrenergic stimulation increases blood vessel tone in mammals. This process involves a number of intracellular signaling pathways that include signaling via phospholipase C, diacylglycerol (DAG), and protein kinase C. So far, it is not certain whether signaling via phospholipase D (PLD) and PLD-derived DAG is involved in this process. We asked whether PLD participates in the ?1-adrenergic-mediated signaling in vascular smooth muscle. ?1-Adrenergic-induced contraction was assessed by myography...    »
 
Journal title abbreviation:
FASEB J 
Year:
2014 
Journal volume:
28 
Journal issue:
Pages contribution:
1044-8 
Language:
eng 
Print-ISSN:
0892-6638 
TUM Institution:
Institut für Pharmakologie und Toxikologie