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Document type:
journal article 
Author(s):
Leiss, Veronika; Illison, Julia; Domes, Katrin; Hofmann, Franz; Lukowski, Robert 
Title:
Expression of cGMP-dependent protein kinase type I in mature white adipocytes. 
Abstract:
The presence of cGMP-dependent protein kinase I (cGKI) in murine adipocytes has been questioned, although cGKI was implicated in the thermogenic program of fat cells (FCs) and to exert anti-hypertrophic/-inflammatory effects in white adipose tissue. Herein, cGKI was detected in adipocytes from control mice, whereas FCs from global cGKI knockouts (cGKI(-/-)) and cGKI? rescue (?RM) mice remained cGKI-negative. cGKI mutants exhibit decreased adipocyte size, plasma leptin levels and reduced body-wei...    »
 
Journal title abbreviation:
Biochem Biophys Res Commun 
Year:
2014 
Journal volume:
452 
Journal issue:
Pages contribution:
151-6 
Language:
eng 
Print-ISSN:
0006-291X 
TUM Institution:
Institut für Pharmakologie und Toxikologie