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Dokumenttyp:
journal article 
Autor(en):
Dunkel, Johannes; Aguilar-Pimentel, Juan Antonio; Ollert, Markus; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrab?; Jalkanen, Sirpa; Salmi, Marko; Veres, Tibor Z 
Titel:
Endothelial amine oxidase AOC3 transiently contributes to adaptive immune responses in the airways. 
Abstract:
Amine oxidase, copper containing 3 (AOC3, also known as vascular adhesion protein-1 (VAP-1)) is an endothelial adhesion molecule that contributes to the extravasation of neutrophils, macrophages, and lymphocytes to sites of inflammation. However, the role of AOC3/VAP-1 in allergic responses remains unknown. Here, we studied eosinophil and CD4+ T-cell recruitment to the airways using AOC3/VAP-1-deficient mice. In an OVA-triggered asthma model, AOC3/VAP-1 slightly contributed to the accumulation o...    »
 
Zeitschriftentitel:
Eur J Immunol 
Jahr:
2014 
Band / Volume:
44 
Heft / Issue:
11 
Seitenangaben Beitrag:
3232-9 
Sprache:
eng 
Print-ISSN:
0014-2980 
TUM Einrichtung:
Institut für Molekulare Allergologie und Umweltforschung; Klinik und Poliklinik für Dermatologie und Allergologie