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Document type:
journal article 
Author(s):
Turvey, Stuart E; Durandy, Anne; Fischer, Alain; Fung, Shan-Yu; Geha, Raif S; Gewies, Andreas; Giese, Thomas; Greil, Johann; Keller, Bärbel; McKinnon, Margaret L; Neven, Bénédicte; Rozmus, Jacob; Ruland, Jürgen; Snow, Andrew L; Stepensky, Polina; Warnatz, Klaus 
Title:
The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency. 
Abstract:
Next-generation DNA sequencing has accelerated the genetic characterization of many human primary immunodeficiency diseases (PIDs). These discoveries can be lifesaving for the affected patients and also provide a unique opportunity to study the effect of specific genes on human immune function. In the past 18 months, a number of independent groups have begun to define novel PIDs caused by defects in the caspase recruitment domain family, member 11 (CARD11)-B-cell chronic lymphocytic leukemia/lym...    »
 
Journal title abbreviation:
J Allergy Clin Immunol 
Year:
2014 
Journal volume:
134 
Journal issue:
Pages contribution:
276-84 
Language:
eng 
Print-ISSN:
0091-6749 
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie