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Document type:
journal article 
Author(s):
Hirsch, Nuria M; Toth, Vivien; Förschler, Annette; Kooijman, Hendrik; Zimmer, Claus; Preibisch, Christine 
Title:
Technical considerations on the validity of blood oxygenation level-dependent-based MR assessment of vascular deoxygenation. 
Abstract:
A blood oxygenation level-dependent (BOLD)-based apparent relative oxygen extraction fraction (rOEF) as a semi-quantitative marker of vascular deoxygenation has recently been introduced in clinical studies of patients with glioma and stroke, yielding promising results. These rOEF measurements are based on independent quantification of the transverse relaxation times T2 and T2* and relative cerebral blood volume (rCBV). Simulations demonstrate that small errors in any of the underlying measures m...    »
 
Journal title abbreviation:
NMR Biomed 
Year:
2014 
Journal volume:
27 
Journal issue:
Pages contribution:
853-62 
Language:
eng 
Print-ISSN:
0952-3480 
TUM Institution:
Abteilung für Neuroradiologie