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Document type:
journal article 
Author(s):
Engel, Katharina; Rudelius, Martina; Meinel, Felix G; Peschel, Christian; Keller, Ulrich 
Title:
An adult patient with Nijmegen Breakage Syndrome and Hodgkin's Lymphoma. 
Abstract:
Nijmegen Breakage Syndrome (NBS) is a rare autosomal recessive DNA repair disorder characterized by immune deficiency, microcephaly, mental retardation and a disposition for the development of hematological malignancies. So far, mostly pediatric patients have been described, since the underlying condition is often fatal before adulthood. Many patients diagnosed with Hodgkin lymphoma (HL) due to this DNA repair defect receive reduced treatment followed by early progression and fatal outcome.We de...    »
 
Journal title abbreviation:
BMC Hematol 
Year:
2014 
Journal volume:
14 
Journal issue:
Pages contribution:
Language:
eng 
TUM Institution:
III. Medizinische Klinik und Poliklinik