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Dokumenttyp:
journal article 
Autor(en):
Engel, Katharina; Rudelius, Martina; Meinel, Felix G; Peschel, Christian; Keller, Ulrich 
Titel:
An adult patient with Nijmegen Breakage Syndrome and Hodgkin's Lymphoma. 
Abstract:
Nijmegen Breakage Syndrome (NBS) is a rare autosomal recessive DNA repair disorder characterized by immune deficiency, microcephaly, mental retardation and a disposition for the development of hematological malignancies. So far, mostly pediatric patients have been described, since the underlying condition is often fatal before adulthood. Many patients diagnosed with Hodgkin lymphoma (HL) due to this DNA repair defect receive reduced treatment followed by early progression and fatal outcome.We de...    »
 
Zeitschriftentitel:
BMC Hematol 
Jahr:
2014 
Band / Volume:
14 
Heft / Issue:
Seitenangaben Beitrag:
Sprache:
eng 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik