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Dokumenttyp:
journal article 
Autor(en):
Jäger, Julia; Greiner, Vera; Strzoda, Daniela; Seibert, Oksana; Niopek, Katharina; Sijmonsma, Tjeerd P; Schäfer, Michaela; Jones, Allan; De Guia, Roldan; Martignoni, Marc; Dallinga-Thie, Geesje M; Diaz, Mauricio B; Hofmann, Thomas G; Herzig, Stephan 
Titel:
Hepatic transforming growth factor-? 1 stimulated clone-22 D1 controls systemic cholesterol metabolism. 
Abstract:
Disturbances in lipid homeostasis are hallmarks of severe metabolic disorders and their long-term complications, including obesity, diabetes, and atherosclerosis. Whereas elevation of triglyceride (TG)-rich very-low-density lipoproteins (VLDL) has been identified as a risk factor for cardiovascular complications, high-density lipoprotein (HDL)-associated cholesterol confers atheroprotection under obese and/or diabetic conditions. Here we show that hepatocyte-specific deficiency of transcription...    »
 
Zeitschriftentitel:
Mol Metab 
Jahr:
2014 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
155-66 
Sprache:
eng 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik