Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Huber, K; Aichler, M; Sun, N; Buck, A; Li, Z; Fernandez, I E; Hauck, S M; Zitzelsberger, H; Eickelberg, O; Janssen, K P; Keller, U; Walch, A 
Titel:
A rapid ex vivo tissue model for optimising drug detection and ionisation in MALDI imaging studies. 
Abstract:
The aim of this study was to establish an ex vivo model for a faster optimisation of sample preparation procedures, for example matrix choice, in matrix-assisted laser desorption/ionisation (MALDI) drug imaging studies. The ionisation properties of four drugs, afatinib, erlotinib, irinotecan and pirfenidone, were determined in an ex vivo tissue experiment by spotting decreasing dilution series onto liver sections. Hereby, the drug signals were distinctly detectable using different matrix compoun...    »
 
Zeitschriftentitel:
Histochem Cell Biol 
Jahr:
2014 
Band / Volume:
142 
Heft / Issue:
Seitenangaben Beitrag:
361-71 
Sprache:
eng 
Print-ISSN:
0948-6143 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik; III. Medizinische Klinik und Poliklinik