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Document type:
journal article 
Author(s):
Berod, Luciana; Stüve, Philipp; Swallow, Maxine; Arnold-Schrauf, Catharina; Kruse, Friederike; Gentilini, Maria V; Freitag, Jenny; Holzmann, Bernhard; Sparwasser, Tim 
Title:
MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection. 
Abstract:
Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis that is responsible for almost 1.5 million deaths per year. Sensing of mycobacteria by the host's immune system relies on different families of receptors present on innate immune cells. Amongst them, several members of the TLR family are involved in the activation of immune cells by mycobacteria, yet the in vivo contribution of individual TLRs to the protective immune response remains controversial. On the contrary...    »
 
Journal title abbreviation:
Eur J Immunol 
Year:
2014 
Journal volume:
44 
Journal issue:
Pages contribution:
1399-409 
Language:
eng 
Print-ISSN:
0014-2980 
TUM Institution:
Chirurgiesche Klinik und Poliklinik