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Dokumenttyp:
journal article 
Autor(en):
Berod, Luciana; Stüve, Philipp; Swallow, Maxine; Arnold-Schrauf, Catharina; Kruse, Friederike; Gentilini, Maria V; Freitag, Jenny; Holzmann, Bernhard; Sparwasser, Tim 
Titel:
MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection. 
Abstract:
Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis that is responsible for almost 1.5 million deaths per year. Sensing of mycobacteria by the host's immune system relies on different families of receptors present on innate immune cells. Amongst them, several members of the TLR family are involved in the activation of immune cells by mycobacteria, yet the in vivo contribution of individual TLRs to the protective immune response remains controversial. On the contrary...    »
 
Zeitschriftentitel:
Eur J Immunol 
Jahr:
2014 
Band / Volume:
44 
Heft / Issue:
Seitenangaben Beitrag:
1399-409 
Sprache:
eng 
Print-ISSN:
0014-2980 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik