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Document type:
journal article 
Author(s):
Petersen, Svea, S; Strohbach, Anne, A; Busch, Raila, R; Felix, Stephan B, SB; Schmitz, Klaus-Peter, KP; Sternberg, Katrin, K 
Title:
Site-selective immobilization of anti-CD34 antibodies to poly(l-lactide) for endovascular implant surfaces. 
Abstract:
Aiming at a speed up of the re-endothelialization process of biodegradable endovascular implants, novel approaches for the functionalization of poly(l-lactide) (PLLA) with anti-CD34 antibodies were established. We propose a three-step process involving PLLA surface activation with functional amino groups, attachment of a protein repelling peptide spacer, and covalent random or site-selective immobilization of the antibodies. Obtainable antibody surface densities and antigen binding capacities we...    »
 
Journal title abbreviation:
J Biomed Mater Res B Appl Biomater 
Year:
2014 
Journal volume:
102 
Journal issue:
Pages contribution:
345-55 
Language:
eng 
Print-ISSN:
1552-4973 
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie