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Dokumenttyp:
journal article 
Autor(en):
Weisser, Martin; Yeh, Ru-Fang; Duchateau-Nguyen, Guillemette; Palermo, Giuseppe; Nguyen, Tri Quang; Shi, Xiaoyan; Stinson, Susanna Y; Yu, Nancy; Dufour, Annika; Robak, Tadeusz; Salogub, Galina N; Dmoszynska, Anna; Solal-Celigny, Philippe; Warzocha, Krzysztof; Loscertales, Javier; Catalano, John; Larratt, Loree; Rossiev, Viktor A; Bence-Bruckler, Isabelle; Geisler, Christian H; Montillo, Marco; Fischer, Kirsten; Fink, Anna-Maria; Hallek, Michael; Bloehdorn, Johannes; Busch, Raymonde; Benner, Axel...    »
 
Titel:
PTK2 expression and immunochemotherapy outcome in chronic lymphocytic leukemia. 
Abstract:
Addition of rituximab (R) to fludarabine and cyclophosphamide (FC) has significantly improved patient outcomes in chronic lymphocytic leukemia (CLL). Whether baseline gene expression can identify patients who will benefit from immunochemotherapy over chemotherapy alone has not been determined. We assessed genome-wide expression of 300 pretreatment specimens from a subset of 552 patients in REACH, a study of FC or R-FC in relapsed CLL. An independent test set was derived from 282 pretreatment spe...    »
 
Zeitschriftentitel:
Blood 
Jahr:
2014 
Band / Volume:
124 
Heft / Issue:
Seitenangaben Beitrag:
420-5 
Sprache:
eng 
Print-ISSN:
0006-4971 
TUM Einrichtung:
Institut für Medizinische Statistik und Epidemiologie