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Document type:
journal article 
Author(s):
Gehrmann, Mathias; Cervello, Melchiorre; Montalto, Giuseppe; Cappello, Francesco; Gulino, Alessandro; Knape, Clemens; Specht, Hanno M; Multhoff, Gabriele 
Title:
Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. 
Abstract:
Members of the heat shock protein 70 (HSP70) family play an important role in assisting protein folding, preventing protein aggregation and transport of proteins across membranes under physiological conditions. Following environmental (i.e., irradiation, chemotherapy), physiological (i.e., cell growth, differentiation), and pathophysiological (i.e., inflammation, tumorigenesis) stress, the synthesis of heat shock proteins (HSPs) is highly up-regulated, whereas protein synthesis in general is red...    »
 
Journal title abbreviation:
Front Immunol 
Year:
2014 
Journal volume:
Pages contribution:
307 
Language:
eng 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie