Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Vaupel, Peter; Mayer, Arnulf 
Titel:
Hypoxia in tumors: pathogenesis-related classification, characterization of hypoxia subtypes, and associated biological and clinical implications. 
Abstract:
Hypoxia is a hallmark of tumors leading to (mal-)adaptive processes, development of aggressive phenotypes and treatment resistance. Based on underlying mechanisms and their duration, two main types of hypoxia have been identified, coexisting with complex spatial and temporal heterogeneities. Chronic hypoxia is mainly caused by diffusion limitations due to enlarged diffusion distances and adverse diffusion geometries (e.g., concurrent vs. countercurrent microvessels, Krogh- vs. Hill-type diffusio...    »
 
Zeitschriftentitel:
Adv Exp Med Biol 
Jahr:
2014 
Band / Volume:
812 
Seitenangaben Beitrag:
19-24 
Sprache:
eng 
Print-ISSN:
0065-2598 
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie