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Document type:
journal article 
Author(s):
Uhl, Matthias; Edler, Lutz; Jensen, Alexandra D; Habl, Gregor; Oelmann, Jan; Röder, Falk; Jäckel, Oliver; Debus, Jürgen; Herfarth, Klaus 
Title:
Randomized phase II trial of hypofractionated proton versus carbon ion radiation therapy in patients with sacrococcygeal chordoma-the ISAC trial protocol. 
Abstract:
Chordomas are relatively rare lesions of the bones. About 30% occur in the sacrococcygeal region. Surgical resection is still the standard treatment. Due to the size, proximity to neurovascular structures and the complex anatomy of the pelvis, a complete resection with adequate safety margin is difficult to perform. A radical resection with safety margins often leads to the loss of bladder and rectal function as well as motoric/sensoric dysfunction. The recurrence rate after surgery alone is com...    »
 
Journal title abbreviation:
Radiat Oncol 
Year:
2014 
Journal volume:
Pages contribution:
100 
Language:
eng 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie