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Document type:
journal article 
Author(s):
Potthoff, Karin; Habl, Gregor; Bruckner, Thomas; Suppan, Christian; Hassel, Jessica; Jäger, Dirk; Indorf, Martin; Debus, Juergen 
Title:
Randomized controlled trial to evaluate the effects of ethyl-2-cyanoacrylate on pain intensity and quality of life in head and neck cancer patients suffering from cetuximab-induced rhagades during radioimmunotherapy: the support trial. 
Abstract:
Cetuximab is a chimeric monoclonal antibody against the epidermal growth factor receptor (EGFR). Skin reactions are the most common side effects of cetuximab. Rhagades of the tips of the fingers and toes, the heels and especially the interphalangeal joints are one of the most frightening and painful dermatological side effects that may develop from EGFR-inhibitor therapy. Rhagades are characterized by pain, severe tenderness and poor healing response. They are challenging to treat. Thus, rhagade...    »
 
Journal title abbreviation:
BMC Cancer 
Year:
2014 
Journal volume:
14 
Pages contribution:
270 
Language:
eng 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie