Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Rieken, Stefan; Simon, Florian; Habermehl, Daniel; Dittmar, Jan Oliver; Combs, Stephanie E; Weber, Klaus; Debus, Jürgen; Lindel, Katja 
Titel:
Photon-induced cell migration and integrin expression promoted by DNA integration of HPV16 genome. 
Abstract:
Persistent human papilloma virus 16 (HPV16) infections are a major cause of cervical cancer. The integration of the viral DNA into the host genome causes E2 gene disruption which prevents apoptosis and increases host cell motility. In cervical cancer patients, survival is limited by local infiltration and systemic dissemination. Surgical control rates are poor in cases of parametrial infiltration. In these patients, radiotherapy (RT) is administered to enhance local control. However, photon irra...    »
 
Zeitschriftentitel:
Strahlenther Onkol 
Jahr:
2014 
Band / Volume:
190 
Heft / Issue:
10 
Seitenangaben Beitrag:
944-9 
Sprache:
eng 
Print-ISSN:
0179-7158 
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie