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Document type:
journal article 
Author(s):
Rieken, Stefan; Simon, Florian; Habermehl, Daniel; Dittmar, Jan Oliver; Combs, Stephanie E; Weber, Klaus; Debus, Jürgen; Lindel, Katja 
Title:
Photon-induced cell migration and integrin expression promoted by DNA integration of HPV16 genome. 
Abstract:
Persistent human papilloma virus 16 (HPV16) infections are a major cause of cervical cancer. The integration of the viral DNA into the host genome causes E2 gene disruption which prevents apoptosis and increases host cell motility. In cervical cancer patients, survival is limited by local infiltration and systemic dissemination. Surgical control rates are poor in cases of parametrial infiltration. In these patients, radiotherapy (RT) is administered to enhance local control. However, photon irra...    »
 
Journal title abbreviation:
Strahlenther Onkol 
Year:
2014 
Journal volume:
190 
Journal issue:
10 
Pages contribution:
944-9 
Language:
eng 
Print-ISSN:
0179-7158 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie