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Document type:
journal article 
Author(s):
Wiestler, Benedikt; Radbruch, Alexander; Osswald, Matthias; Combs, Stephanie E; Jungk, Christine; Winkler, Frank; Bendszus, Martin; Unterberg, Andreas; Platten, Michael; Wick, Wolfgang; Wick, Antje 
Title:
Towards optimizing the sequence of bevacizumab and nitrosoureas in recurrent malignant glioma. 
Abstract:
Studies on the monoclonal VEGF-A antibody bevacizumab gave raise to questions regarding the lack of an overall survival benefit, the optimal timing in the disease course and potential combination and salvage therapies. We retrospectively assessed survival, radiological progression type on bevacizumab and efficacy of salvage therapies in 42 patients with recurrent malignant gliomas who received bevacizumab and nitrosourea sequentially. 15 patients received bevacizumab followed by nitrosourea at p...    »
 
Journal title abbreviation:
J Neurooncol 
Year:
2014 
Journal volume:
117 
Journal issue:
Pages contribution:
85-92 
Language:
eng 
Print-ISSN:
0167-594X 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie