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Dokumenttyp:
journal article 
Autor(en):
Altomonte, Jennifer; Ebert, Oliver 
Titel:
Sorting Out Pandora's Box: Discerning the Dynamic Roles of Liver Microenvironment in Oncolytic Virus Therapy for Hepatocellular Carcinoma. 
Abstract:
Oncolytic viral therapies have recently found their way into clinical application for hepatocellular carcinoma (HCC), a disease with limited treatment options and poor prognosis. Adding to the many intrinsic challenges of in vivo oncolytic viral therapy, is the complex microenvironment of the liver, which imposes unique limitations to the successful delivery and propagation of the virus. The normal liver milieu is characterized by an intricate network of hepatocytes and non-parenchymal cells inc...    »
 
Zeitschriftentitel:
Front Oncol 
Jahr:
2014 
Band / Volume:
Seitenangaben Beitrag:
85 
Sprache:
eng 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik