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Document type:
journal article 
Author(s):
Altomonte, Jennifer; Ebert, Oliver 
Title:
Sorting Out Pandora's Box: Discerning the Dynamic Roles of Liver Microenvironment in Oncolytic Virus Therapy for Hepatocellular Carcinoma. 
Abstract:
Oncolytic viral therapies have recently found their way into clinical application for hepatocellular carcinoma (HCC), a disease with limited treatment options and poor prognosis. Adding to the many intrinsic challenges of in vivo oncolytic viral therapy, is the complex microenvironment of the liver, which imposes unique limitations to the successful delivery and propagation of the virus. The normal liver milieu is characterized by an intricate network of hepatocytes and non-parenchymal cells inc...    »
 
Journal title abbreviation:
Front Oncol 
Year:
2014 
Journal volume:
Pages contribution:
85 
Language:
eng 
TUM Institution:
II. Medizinische Klinik und Poliklinik