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Dokumenttyp:
journal article 
Autor(en):
Hoffmann, Ulrike; Grosse-Sundrup, Martina; Eikermann-Haerter, Katharina; Zaremba, Sebastina; Ayata, Cenk; Zhang, Ben; Ma, Da; Isaacs, Lyle; Eikermann, Matthias 
Titel:
Calabadion: A new agent to reverse the effects of benzylisoquinoline and steroidal neuromuscular-blocking agents. 
Abstract:
To evaluate whether calabadion 1, an acyclic member of the Cucurbit[n]uril family of molecular containers, reverses benzylisoquinoline and steroidal neuromuscular-blocking agent effects.A total of 60 rats were anesthetized, tracheotomized, and instrumented with IV and arterial catheters. Rocuronium (3.5 mg/kg) or cisatracurium (0.6 mg/kg) was administered and neuromuscular transmission quantified by acceleromyography. Calabadion 1 at 30, 60, and 90 mg/kg (for rocuronium) or 90, 120, and 150 mg/k...    »
 
Zeitschriftentitel:
Anesthesiology 
Jahr:
2013 
Band / Volume:
119 
Heft / Issue:
Seitenangaben Beitrag:
317-25 
Sprache:
eng 
Print-ISSN:
0003-3022 
TUM Einrichtung:
Klinik für Anästhesiologie