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Dokumenttyp:
journal article 
Autor(en):
Haseneder, Rainer; Starker, Laura; Berkmann, Jasmin; Kellermann, Kristine; Jungwirth, Bettina; Blobner, Manfred; Eder, Matthias; Kochs, Eberhard; Rammes, Gerhard 
Titel:
Sevoflurane anesthesia improves cognitive performance in mice, but does not influence in vitro long-term potentation in hippocampus CA1 stratum radiatum. 
Abstract:
Whether the occurrence of postoperative cognitive dysfunction is a result of the effects of surgery or anesthesia is under debate. In this study, we investigated the impact of sevoflurane anesthesia on cognitive performance and cellular mechanisms involved in learning and memory.Male C57Bl6/J mice (4-5 months) were exposed to one minimum alveolar concentration sevoflurane for two hours. After 24 h, cognitive performance of mice was assessed using the modified hole board test. Additionally, we ev...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2013 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e64732 
Sprache:
eng 
TUM Einrichtung:
Klinik für Anästhesiologie