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Dokumenttyp:
journal article 
Autor(en):
Ringelhan, Marc, M; Protzer, Ulrike, U; O'Connor, Tracy, T; Heikenwalder, Mathias, M 
Titel:
The direct and indirect role of HBV in liver cancer: Prospective markers for HCC-screening and potential therapeutic targets. 
Abstract:
Chronic Hepatitis B virus (HBV) infection remains the number one risk factor for hepatocellular carcinoma (HCC), accounting for more than 600000 deaths per year. Despite highly effective antiviral treatment options, chronic hepatitis B (CHB), subsequent end stage liver disease and HCC development remain a major challenge worldwide. In CHB, liver damage is mainly caused by the influx of immune cells and destruction of infected hepatocytes causing necroinflammation. Treatment with nucleos(t)id ana...    »
 
Zeitschriftentitel:
J Pathol 
Jahr:
2014 
Sprache:
eng 
Print-ISSN:
0022-3417 
TUM Einrichtung:
r Virologie