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Dokumenttyp:
journal article 
Autor(en):
Bergmann, Frank; Aulmann, Sebastian; Sipos, Bence; Kloor, Matthias; von Heydebreck, Anja; Schweipert, Johannes; Harjung, Andreas; Mayer, Philipp; Hartwig, Werner; Moldenhauer, Gerhard; Capper, David; Dyckhoff, Gerhard; Freier, Kolja; Herpel, Esther; Schleider, Anja; Schirmacher, Peter; Mechtersheimer, Gunhild; Klöppel, Günter; Bläker, Hendrik 
Titel:
Acinar cell carcinomas of the pancreas: a molecular analysis in a series of 57 cases. 
Abstract:
Pancreatic acinar cell carcinomas (PACs) are rare but are distinct aggressive neoplasms that phenotypically differ from pancreatic ductal adenocarcinomas (PDACs) and pancreatic neuroendocrine neoplasms (PNENs). Despite recent work on the genetic changes of PACs, their molecular pathogenesis is still poorly understood. In this study, we focus on a comparative genomic hybridization analysis. Based on frequent chromosomal imbalances, the involvement of DCC and c-MYC in the pathogenesis of PACs is f...    »
 
Zeitschriftentitel:
Virchows Arch 
Jahr:
2014 
Band / Volume:
465 
Heft / Issue:
Seitenangaben Beitrag:
661-72 
Sprache:
eng 
Print-ISSN:
0945-6317 
TUM Einrichtung:
Institut für Allgemeine Pathologie und pathologische Anatomie