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Document type:
journal article 
Author(s):
Lemcke, Susanne; Müller, Susen; Möller, Steffen; Schillert, Arne; Ziegler, Andreas; Cepok-Kauffeld, Sabine; Comabella, Manuel; Montalban, Xavier; Rülicke, Thomas; Nandakumar, Kutty Selva; Hemmer, Bernhard; Holmdahl, Rikard; Pahnke, Jens; Ibrahim, Saleh M 
Title:
Nerve conduction velocity is regulated by the inositol polyphosphate-4-phosphatase II gene. 
Abstract:
Impairment of nerve conduction is common in neurodegenerative and neuroinflammatory diseases such as multiple sclerosis (MS), and measurement of evoked potentials (visual, motor, or sensory) has been widely used for diagnosis and recently also as a prognostic marker for MS. We used a classical genetic approach to identify novel genes controlling nerve conduction. First, we used quantitative trait mapping in F2 progeny of B10/SJL mice to identify EAE31, a locus controlling latency of motor evoked...    »
 
Journal title abbreviation:
Am J Pathol 
Year:
2014 
Journal volume:
184 
Journal issue:
Pages contribution:
2420-9 
Language:
eng 
Print-ISSN:
0002-9440 
TUM Institution:
Neurologische Klinik und Poliklinik