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Document type:
journal article 
Author(s):
Thibaudeau, Laure; Quent, Verena M; Holzapfel, Boris M; Taubenberger, Anna V; Straub, Melanie; Hutmacher, Dietmar W 
Title:
Mimicking breast cancer-induced bone metastasis in vivo: current transplantation models and advanced humanized strategies. 
Abstract:
Bone metastasis is a complication that occurs in 80 % of women with advanced breast cancer. Despite the prevalence of bone metastatic disease, the avenues for its clinical management are still restricted to palliative treatment options. In fact, the underlying mechanisms of breast cancer osteotropism have not yet been fully elucidated due to a lack of suitable in vivo models that are able to recapitulate the human disease. In this work, we review the current transplantation-based models to inves...    »
 
Journal title abbreviation:
Cancer Metastasis Rev 
Year:
2014 
Journal volume:
33 
Journal issue:
2-3 
Pages contribution:
721-35 
Language:
eng 
Print-ISSN:
0167-7659 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie