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Dokumenttyp:
journal article 
Autor(en):
Aichler, Michaela; Motschmann, Martin; Jütting, Uta; Luber, Birgit; Becker, Karen; Ott, Katja; Lordick, Florian; Langer, Rupert; Feith, Marcus; Siewert, Jörg Rüdiger; Walch, Axel 
Titel:
Epidermal growth factor receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy. 
Abstract:
Neoadjuvant platin-based therapy is accepted as a standard therapy for advanced esophageal adenocarcinoma (EAC). Patients who respond have a better survival prognosis, but still a significant number of responder patients die from tumor recurrence. Molecular markers for prognosis in neoadjuvantly treated EAC patients have not been identified yet. We investigated the epidermal growth factor receptor (EGFR) in prognosis and chemotherapy resistance in these patients. Two EAC patient cohorts, either...    »
 
Zeitschriftentitel:
Oncotarget 
Jahr:
2014 
Band / Volume:
Heft / Issue:
16 
Seitenangaben Beitrag:
6620-32 
Sprache:
eng 
TUM Einrichtung:
Institut für Allgemeine Pathologie und pathologische Anatomie; Chirurgiesche Klinik und Poliklinik