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Dokumenttyp:
journal article 
Autor(en):
Wildgruber, M; Bielicki, I; Aichler, M; Kosanke, K; Feuchtinger, A; Settles, M; Onthank, DC; Cesati, RR; Robinson, SP; Huber, AM; Rummeny, EJ; Walch, AK; Botnar, RM 
Titel:
Assessment of myocardial infarction and postinfarction scar remodeling with an elastin-specific magnetic resonance agent. 
Abstract:
To prospectively evaluate an elastin-specific MR contrast agent (ESMA) for in vivo targeting of elastic fibers in myocardial infarction (MI) and postinfarction scar remodeling.MI was induced in C57BL/6J mice (n=40) by permanent ligation of the left anterior descending coronary artery. MRI was performed at 7 and 21 days after MI. The merits of gadolinium-based ESMA (Gd-ESMA) were compared with gadopentetic acid (Gd-DTPA) for infarct size determination, contrast-to-noise ratio (CNR), and enhanceme...    »
 
Zeitschriftentitel:
Circ Cardiovasc Imaging 
Jahr:
2014 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
321-9 
Sprache:
eng 
Print-ISSN:
1941-9651 
TUM Einrichtung:
r Radiologie