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Dokumenttyp:
journal article 
Autor(en):
Li, D; Beisswenger, C; Herr, C; Schmid, R M; Gallo, R L; Han, G; Zakharkina, T; Bals, R 
Titel:
Expression of the antimicrobial peptide cathelicidin in myeloid cells is required for lung tumor growth. 
Abstract:
Antimicrobial peptides, such as the cathelicidin LL-37/hCAP-18 and its mouse homolog cathelicidin-related antimicrobial peptide (CRAMP), are important effectors of the innate immune system with direct anti-bacterial activity. Cathelicidin is possibly involved in the regulation of tumor cell growth. The aim of this study was to characterize the role of cathelicidin expressed in non-tumorous cells in a preclinical mouse model of tumor growth. Wild-type and CRAMP-deficient animals were exposed to c...    »
 
Zeitschriftentitel:
Oncogene 
Jahr:
2014 
Band / Volume:
33 
Heft / Issue:
21 
Seitenangaben Beitrag:
2709-16 
Sprache:
eng 
Print-ISSN:
0950-9232 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik