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Author(s):
Ahrens, Birgit; Quarcoo, David; Buhner, Sabine; Matricardi, Paolo M.; Hamelmann, Eckard 
Title:
Oral Administration of Bacterial Lysates Attenuates Experimental Food Allergy 
Abstract:
Background: Modulating early immune response by application of bacteria and their by-products has been suggested as a preventive strategy against the development of allergic diseases. In light of this, the aim of the study was to test the effects of oral administration of bacterial lysates (BL) in a rat model of food allergy. Methods: BL or PBS were administered orally to neonatal Brown Norway rats up to an age of 42 days. Additionally, animals were sensitized 3 times (days 35, 40 and 45) intrap...    »
 
Keywords:
Food allergy; Bacterial lysates; Immune modulation; Primary prevention; Innate immunity 
Journal title:
International Archives of Allergy and Immunology 
Year:
2011 
Journal volume:
156 
Journal issue:
Pages contribution:
196--204 
Publisher:
S. Karger AG 
Publisher address:
Basel, Switzerland 
Print-ISSN:
1423-0097 
E-ISSN:
1423-0097 
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.