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Author(s):
Besig, Sophie; Voland, Petra; Baur, Dorothee M.; Perren, Aurel; Prinz, Christian 
Title:
Vascular Endothelial Growth Factors, Angiogenesis, and Survival in Human Ileal Enterochromaffin Cell Carcinoids 
Abstract:
Background and Aims: Well-differentiated neuro-endocrine ileal carcinoids are composed of serotonin-producing enterochromaffin (EC) cells. Life expectancy is determined by metastatic spread to the liver because medical treatment options are still very limited. Selective inhibition of angiogenesis or lymphangiogenesis might prevent tumour growth and metastatic spread. We examined the role of the vascular endothelial growth factors (VEGFs) A, B, C, D, and their receptors (VEGFRs) 1, 2, 3 in angiog...    »
 
Keywords:
Enterochromaffin cell; Carcinoid; Vascular endothelial growth factor; Angiogenesis 
Journal title:
Neuroendocrinology 
Year:
2009 
Journal volume:
90 
Journal issue:
Pages contribution:
402--415 
Fulltext / DOI:
Publisher:
S. Karger AG 
Publisher address:
Basel, Switzerland 
Print-ISSN:
1423-0194 
E-ISSN:
1423-0194 
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.