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Document type:
Zeitschriftenaufsatz 
Author(s):
Walch, Axel; Komminoth, Paul; Hutzler, Peter; Aubele, Michaela; Höfler, Heinz; Werner, Martin 
Title:
Microdissection of Tissue Sections: Application to the Molecular Genetic Characterisation of Premalignant Lesions 
Abstract:
The characterisation of the early molecular genetic events of tumor development depends on the selective procurement of histopathologically defined small cell populations from premalignant tissue. In order to obtain high-quality DNA, mRNA and proteins from these small tissue samples and even from single cells, tissue microdissection is one of the most useful techniques, becoming increasingly important for molecular pathologists. Using different microdissection techniques which allow the isolatio...    »
 
Keywords:
Microdissection of tissue; Lesions; premalignant; DNA; mRNA; Proteins; Genomic analysis; Molecular pathology; Array technology 
Journal title:
Pathobiology 
Year:
2000 
Journal volume:
68 
Journal issue:
Pages contribution:
9--17 
Publisher:
S. Karger AG 
Publisher address:
Basel, Switzerland 
Print-ISSN:
1423-0291 
E-ISSN:
1423-0291 
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.