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Autor(en):
Prakash, Nilima; Wurst, Wolfgang 
Titel:
A Wnt Signal Regulates Stem Cell Fate and Differentiation in vivo 
Abstract:
Our knowledge about the normal generation of midbrain dopaminergic neurons in vivois still rudimentary, despite many attempts to recapitulate the underlying events in vitro. Because the loss of these neurons is implicated in Parkinson’s disease, this lack of information is one of the major drawbacks in the development of better therapies for this severe human neurological disorder. Recently, substantial advances have been made by demonstrating that the secreted molecule Wnt1 regulates a genetic...    »
 
Stichworte:
Parkinson’ s disease; Dopamine neuron; Ventral midbrain 
Zeitschriftentitel:
Neurodegenerative Diseases 
Jahr:
2007 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
333--338 
Verlag / Institution:
S. Karger AG 
Verlagsort:
Basel, Switzerland 
Print-ISSN:
1660-2862 
E-ISSN:
1660-2862 
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.