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Author(s):
Preissler, G.; Massberg, S.; Eichhorn, M. E.; Waldner, H.; Loehe, F.; Winter, H.; Messmer, K. 
Title:
Islets of Langerhans Are Protected from Inflammatory Cell Recruitment during Reperfusion of Rat Pancreas Grafts 
Abstract:
Background: Ischemia/reperfusion (I/R) injury plays a pivotal role in the development of graft pancreatitis, with ischemia time representing one of its crucial factors. However, it is unclear, whether exocrine and endocrine tissue experience similar inflammatory responses during pancreas transplantation (PTx). This study evaluated inflammatory susceptibilities of islets of Langerhans (ILH) and exocrine tissue after different preservation periods during early reperfusion. Methods: PTx was perform...    »
 
Keywords:
Pancreas transplantation; Microcirculation; Leukocytes; Islets of Langerhans; Ischemia/reperfusion 
Journal title:
European Surgical Research 
Year:
2010 
Journal volume:
44 
Journal issue:
3-4 
Pages contribution:
192--200 
Publisher:
S. Karger AG 
Publisher address:
Basel, Switzerland 
Print-ISSN:
1421-9921 
E-ISSN:
1421-9921 
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.