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Autor(en):
Abbrederis, Kathrin; Lorenzen, Sylvie; Rothling, Nadine; Ihbe-Heffinger, Angela; Schuster, Tibor; Peschel, Christian; Lordick, Florian 
Titel:
Chemotherapy-Induced Nausea and Vomiting in the Treatment of Gastrointestinal Tumors and Secondary Prophylaxis with Aprepitant 
Abstract:
Background: Chemotherapy-induced nausea and vomiting (CINV) belongs to the most feared side-effects of cancer treatment. Its incidence during chemotherapy of gastrointestinal tu-mors (GITs) with highly and moderately emetogenic regimens is not well documented. It is also unknown whether aprepitant, a neurokinin-1 receptor antagonist, can be used as secondary antiemetic prophylaxis in case of CINV during cycle 1. Patients and Methods: Patients with GITs who were treated with highly and moderately...    »
 
Stichworte:
Neurokinin-1 receptor; Chemotherapy-induced nausea and vomiting; Gastrointestinal tumors; Aprepitant 
Zeitschriftentitel:
Onkologie 
Jahr:
2009 
Band / Volume:
32 
Heft / Issue:
1-2 
Seitenangaben Beitrag:
30--34 
Verlag / Institution:
S. Karger GmbH 
Verlagsort:
Freiburg, Germany 
Print-ISSN:
1423-0240 
E-ISSN:
2296-5262 
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.