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Dokumenttyp:
journal article 
Autor(en):
Mayer, Arnulf; Vaupel, Peter 
Titel:
Hypoxia, lactate accumulation, and acidosis: siblings or accomplices driving tumor progression and resistance to therapy? 
Abstract:
This chapter briefly summarizes the most important processes by which hypoxia, lactate accumulation, and acidosis may influence malignant progression and therapeutic resistance of solid malignant tumors. While these phenomena are often elements of an integrated reaction, they may occur independently of each other under certain circumstances. The latter information may be of interest with regard to possible "targeted" therapeutic interventions. 
Zeitschriftentitel:
Adv Exp Med Biol 
Jahr:
2013 
Band / Volume:
789 
Seitenangaben Beitrag:
203-9 
Sprache:
eng 
Print-ISSN:
0065-2598 
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie