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Dokumenttyp:
journal article 
Autor(en):
Dauvilliers, Yves; Winkelmann, Juliane 
Titel:
Restless legs syndrome: update on pathogenesis. 
Abstract:
Much recent progress has been made in understanding restless legs syndrome (RLS), focusing mainly on genetic predisposition and dysregulation of iron metabolism and the dopaminergic system. We provide in this review an update of the most recent scientific advances on the pathophysiology of primary RLS.Genome-wide association studies identified six genetic variants including MEIS1 and BTBD9 with potential relationships with iron. Brain iron level is low in RLS and neuropathological studies have s...    »
 
Zeitschriftentitel:
Curr Opin Pulm Med 
Jahr:
2013 
Band / Volume:
19 
Heft / Issue:
Seitenangaben Beitrag:
594-600 
Sprache:
eng 
Print-ISSN:
1070-5287 
TUM Einrichtung:
Neurologische Klinik und Poliklinik