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Document type:
journal article 
Author(s):
Rusai, Krisztina; Prokai, A; Juanxing, C; Meszaros, K; Szalay, B; Pásti, K; Müller, V; Heemann, U; Lutz, J; Tulassay, T; Szabo, A J 
Title:
Dexamethasone protects from renal ischemia/reperfusion injury: a possible association with SGK-1. 
Abstract:
Previous experimental data suggest that steroids might have protective effects during hypoxic/ischemic injury of various organs. In this study, the association between dexamethason (Dexa) treatment and the anti-apoptotic SGK-1 was tested in ischemic renal injury. In vitro, HK-2 cells were exposed to 24 h hypoxia, and the effect of Dexa incubation on SGK-1 expression / activation and on cell death was studied. In an in vivo rat model of unilateral renal IR, animals were treated with Dexa, and ser...    »
 
Journal title abbreviation:
Acta Physiol Hung 
Year:
2013 
Journal volume:
100 
Journal issue:
Pages contribution:
173-85 
Language:
eng 
Print-ISSN:
0231-424X 
TUM Institution:
Abteilung für Nephrologie