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Document type:
journal article 
Author(s):
Wessel, David L; Berger, Felix; Li, Jennifer S; Dähnert, Ingo; Rakhit, Amit; Fontecave, Sylvie; Newburger, Jane W; CLARINET Investigators; Trentadue, Julio; Gutierrez, Diego; Antoni, Diego; Toledo, Ruben; Parodi, Willy Conejeros; Guerrero, Rafael; Klinger, Daniel; Magliola, Ricardo; Mazzucchelli, Maria Teresa; Moreno, Mariano; Bellani, Patricia; Couceiro, Claudia; Marantz, Pablo; Rosselot, Silvina; Benmaor, Lisandro; Elorriaga, Maria Sol; Peña, Gabriela; Somoza, Felipe; Romero, Sandra; Barrea, C...    »
 
Title:
Clopidogrel in infants with systemic-to-pulmonary-artery shunts. 
Abstract:
Infants with cyanotic congenital heart disease palliated with placement of a systemic-to-pulmonary-artery shunt are at risk for shunt thrombosis and death. We investigated whether the addition of clopidogrel to conventional therapy reduces mortality from any cause and morbidity related to the shunt.In a multicenter, double-blind, event-driven trial, we randomly assigned infants 92 days of age or younger with cyanotic congenital heart disease and a systemic-to-pulmonary-artery shunt to receive cl...    »
 
Journal title abbreviation:
N Engl J Med 
Year:
2013 
Journal volume:
368 
Journal issue:
25 
Pages contribution:
2377-84 
Language:
eng 
Print-ISSN:
0028-4793 
TUM Institution:
Klinik für Kinderkardiologie und angeborene Herzfehler