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Dokumenttyp:
journal article 
Autor(en):
Wessel, David L; Berger, Felix; Li, Jennifer S; Dähnert, Ingo; Rakhit, Amit; Fontecave, Sylvie; Newburger, Jane W; CLARINET Investigators; Trentadue, Julio; Gutierrez, Diego; Antoni, Diego; Toledo, Ruben; Parodi, Willy Conejeros; Guerrero, Rafael; Klinger, Daniel; Magliola, Ricardo; Mazzucchelli, Maria Teresa; Moreno, Mariano; Bellani, Patricia; Couceiro, Claudia; Marantz, Pablo; Rosselot, Silvina; Benmaor, Lisandro; Elorriaga, Maria Sol; Peña, Gabriela; Somoza, Felipe; Romero, Sandra; Barrea, C...    »
 
Titel:
Clopidogrel in infants with systemic-to-pulmonary-artery shunts. 
Abstract:
Infants with cyanotic congenital heart disease palliated with placement of a systemic-to-pulmonary-artery shunt are at risk for shunt thrombosis and death. We investigated whether the addition of clopidogrel to conventional therapy reduces mortality from any cause and morbidity related to the shunt.In a multicenter, double-blind, event-driven trial, we randomly assigned infants 92 days of age or younger with cyanotic congenital heart disease and a systemic-to-pulmonary-artery shunt to receive cl...    »
 
Zeitschriftentitel:
N Engl J Med 
Jahr:
2013 
Band / Volume:
368 
Heft / Issue:
25 
Seitenangaben Beitrag:
2377-84 
Sprache:
eng 
Print-ISSN:
0028-4793 
TUM Einrichtung:
Klinik für Kinderkardiologie und angeborene Herzfehler