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Dokumenttyp:
journal article 
Autor(en):
Graf, N; Herrmann, K; Numberger, B; Zwisler, D; Aichler, M; Feuchtinger, A; Schuster, T; Wester, HJ; Senekowitsch-Schmidtke, R; Peschel, C; Schwaiger, M; Keller, U; Dechow, T; Buck, AK 
Titel:
[18F]FLT is superior to [18F]FDG for predicting early response to antiproliferative treatment in high-grade lymphoma in a dose-dependent manner. 
Abstract:
Positron emission tomography (PET) with the thymidine analogue [(18)F]fluorothymidine ([(18)F]FLT) has been shown to detect early response to chemotherapy in high-grade lymphoma. In this preclinical in vitro and in vivo study we compared [(18)F]FLT to the glucose analogue [(18)F]fluorodeoxyglucose ([(18)F]FDG) regarding dose-dependent visualization and prediction of early therapy response.Immunodeficient mice bearing human diffuse large B-cell lymphoma (SUDHL-4) xenotransplants were treated intr...    »
 
Zeitschriftentitel:
Eur J Nucl Med Mol Imaging 
Jahr:
2013 
Band / Volume:
40 
Heft / Issue:
Seitenangaben Beitrag:
34-43 
Sprache:
eng 
Print-ISSN:
1619-7070 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik; Nuklearmedizinische Klinik und Poliklinik