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Dokumenttyp:
journal article 
Autor(en):
Ringelhan, M; Heikenwalder, M; Protzer, U 
Titel:
Direct effects of hepatitis B virus-encoded proteins and chronic infection in liver cancer development. 
Abstract:
Hepatocellular carcinoma (HCC) ranks as the third leading cause of cancer-related death worldwide with currently limited treatment options. Chronic hepatitis B virus (HBV) infection accounts for HCC development in more than 50% of cases. The lifetime risk of HBV carriers to develop cirrhosis, liver failure or HCC is estimated to be as high as 15-40%. Although several pathways and triggers contributing to HCC development have been described, many features of hepatocellular carcinogenesis and the...    »
 
Zeitschriftentitel:
Dig Dis 
Jahr:
2013 
Band / Volume:
31 
Heft / Issue:
Seitenangaben Beitrag:
138-51 
Sprache:
eng 
Print-ISSN:
0257-2753 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik; Institut für Virologie