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Dokumenttyp:
journal article 
Autor(en):
Dahmani, Ch; Mykhaylyk, O; Helling, Fl; Goetz, St; Weyh, Th; Herzog, H-G; Plank, Ch 
Titel:
Rotational magnetic pulses enhance the magnetofection efficiency in vitro in adherent and suspension cells 
Abstract:
The association of magnetic nanoparticles with gene delivery vectors in combination with the use of gradient magnetic fields (magnetofection) enables improved and synchronised gene delivery to cells. In this paper, we report a system comprising rotating permanent magnets to generate defined magnetic field pulses with frequencies from 2.66 to 133 Hz and a field amplitude of 190 or 310 mT at the location of the cells. Low-frequency pulses of 2.66-10 Hz with a magnetic flux density of 190 mT were a...    »
 
Zeitschriftentitel:
Journal of magnetism and magnetic materials 
Jahr:
2013 
Band / Volume:
332 
Seitenangaben Beitrag:
163-171 
Sprache:
eng 
Print-ISSN:
0304-8853 
TUM Einrichtung:
Institut für experimentelle Onkologie und Therapieforschung