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Document type:
journal article 
Author(s):
Harbeck, N; Schmitt, M; Meisner, C; Friedel, C; Untch, M; Schmidt, M; Sweep, C G J; Lisboa, B W; Lux, M P; Beck, T; Hasmüller, S; Kiechle, M; Jänicke, F; Thomssen, C; Chemo-N 0 Study Group; Graeff, H; Harbeck, N; Prechtl, A; Schmitt, M; Jänicke, F; Lisboa, B; Thomssen, C; Hepp, H; Untch, M; Haslmüller, S; Friese, K; Knapstein, P G; Mahlke, M; Schmidt, M; Kölbl, H; Lang, N; Merkle, E; Wieland, G; Lux, M P; Beckmann, M; Hoffmann, G; Scheler, P; Lehnert, A; Kreienberg, R; Möbus, V; Eiermann, W; Ham...    »
 
Title:
Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients. 
Abstract:
Final 10-year analysis of the prospective randomised Chemo-N0 trial is presented. Based on the Chemo-N0 interim results and an European Organisation for Research and Treatment of Cancer (EORTC) pooled analysis (n=8377), American Society of Clinical Oncology (ASCO) and Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) guidelines recommend invasion and metastasis markers urokinase-type plasminogen activator (uPA)/plasminogen activator inhibitor-1 (PAI-1) for risk assessment and treatment decision...    »
 
Journal title abbreviation:
Eur J Cancer 
Year:
2013 
Journal volume:
49 
Journal issue:
Pages contribution:
1825-35 
Language:
eng 
Print-ISSN:
0959-8049 
TUM Institution:
Frauenklinik und Poliklinik; Chirurgiesche Klinik und Poliklinik