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Dokumenttyp:
journal article 
Autor(en):
Wohlleber, D; Kashkar, H; Gärtner, K; Frings, MK; Odenthal, M; Hegenbarth, S; Börner, C; Arnold, B; Hämmerling, G; Nieswandt, B; van Rooijen, N; Limmer, A; Cederbrant, K; Heikenwalder, M; Pasparakis, M; Protzer, U; Dienes, HP; Kurts, C; Krönke, M; Knolle, PA 
Titel:
TNF-induced target cell killing by CTL activated through cross-presentation. 
Abstract:
Viruses can escape cytotoxic T cell (CTL) immunity by avoiding presentation of viral components via endogenous MHC class I antigen presentation in infected cells. Cross-priming of viral antigens circumvents such immune escape by allowing noninfected dendritic cells to activate virus-specific CTLs, but they remain ineffective against infected cells in which immune escape is functional. Here, we show that cross-presentation of antigen released from adenovirus-infected hepatocytes by liver sinusoid...    »
 
Zeitschriftentitel:
Cell Rep 
Jahr:
2012 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
478-87 
Sprache:
eng 
TUM Einrichtung:
r Virologie