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Dokumenttyp:
journal article 
Autor(en):
Schmid, TE; Zlobinskaya, O; Multhoff, G 
Titel:
Differences in Phosphorylated Histone H2AX Foci Formation and Removal of Cells Exposed to Low and High Linear Energy Transfer Radiation. 
Abstract:
The use of particle ion beams in cancer radiotherapy has a long history. Today, beams of protons or heavy ions, predominantly carbon ions, can be accelerated to precisely calculated energies which can be accurately targeted to tumors. This particle therapy works by damaging the DNA of tissue cells, ultimately causing their death. Among the different types of DNA lesions, the formation of DNA double strand breaks is considered to be the most relevant of deleterious damages of ionizing radiation i...    »
 
Zeitschriftentitel:
Curr Genomics 
Jahr:
2012 
Band / Volume:
13 
Heft / Issue:
Seitenangaben Beitrag:
418-25 
Sprache:
eng 
Print-ISSN:
1389-2029 
TUM Einrichtung:
r Strahlentherapie und Radiologische Onkologie