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Document type:
journal article 
Author(s):
Gaertner, FC; Souvatzoglou, M; Brix, G; Beer, AJ 
Title:
Imaging of hypoxia using PET and MRI. 
Abstract:
Tumor hypoxia is the result of an inadequate supply of oxygen to tumor cells which can be caused by multiple factors. It is associated with aggressive local tumor growth and invasion, increased risk of metastasis, higher resistance to radiotherapy (RT) and chemotherapy, overall resulting in a poor clinical prognosis. Many locally advanced solid tumors may exhibit hypoxic and/or anoxic tissue areas that are heterogeneously distributed within the tumor mass. As hypoxia is a negative prognostic fac...    »
 
Journal title abbreviation:
Curr Pharm Biotechnol 
Year:
2012 
Journal volume:
13 
Journal issue:
Pages contribution:
552-70 
Language:
eng 
Print-ISSN:
1389-2010 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik