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Dokumenttyp:
journal article 
Autor(en):
Waubant, E; Pelletier, D; Mass, M; Cohen, JA; Kita, M; Cross, A; Bar-Or, A; Vollmer, T; Racke, M; Stüve, O; Schwid, S; Goodman, A; Kachuck, N; Preiningerova, J; Weinstock-Guttman, B; Calabresi, PA; Miller, A; Mokhtarani, M; Iklé, D; Murphy, S; Kopetskie, H; Ding, L; Rosenberg, E; Spencer, C; Zamvil, SS; ITN STAyCIS Study Group; ITN020AI Study Management Team; Zamvil, SS; Waubant, E; Pelletier, D; Mass, M; Bourdette, D; Egan, R; Cohen, J; Stone, L; Kita, M; Elliott, M; Cross, A; Parks, BJ; Bar-Or...    »
 
Titel:
Randomized controlled trial of atorvastatin in clinically isolated syndrome: the STAyCIS study. 
Abstract:
To test efficacy and safety of atorvastatin in subjects with clinically isolated syndrome (CIS).Subjects with CIS were enrolled in a phase II, double-blind, placebo-controlled, 14-center randomized trial testing 80 mg atorvastatin on clinical and brain MRI activity. Brain MRIs were performed quarterly. The primary endpoint (PEP) was development of>= 3 new T2 lesions, or one clinical relapse within 12 months. Subjects meeting the PEP were offered additional weekly interferon ?-1a (IFN?-1a).Due to...    »
 
Zeitschriftentitel:
Neurology 
Jahr:
2012 
Band / Volume:
78 
Heft / Issue:
15 
Seitenangaben Beitrag:
1171-8 
Sprache:
eng 
Print-ISSN:
0028-3878 
TUM Einrichtung:
Neurologische Klinik und Poliklinik