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Dokumenttyp:
journal article 
Autor(en):
Smolianov, V; Dehmel, T; Kieseier, BC; Hemmer, B; Hartung, HP; Hofstetter, HH 
Titel:
Ex vivo activation of naturally occurring IL-17-producing T cells does not require IL-6. 
Abstract:
Interleukin (IL-)17 is a potent proinflammatory cytokine for which an important role in the immune response against infections and in autoimmune diseases has been demonstrated. Recently, it has been shown that - in addition to mature T cells which are primed in the immune periphery - this cytokine can also be produced by T cells in the thymus, so-called naturally occurring IL-17-producing T cells (nT17 cells). In this study we demonstrate that the generation and activation of nT17 cells in the t...    »
 
Zeitschriftentitel:
Cytokine 
Jahr:
2012 
Band / Volume:
58 
Heft / Issue:
Seitenangaben Beitrag:
231-7 
Sprache:
eng 
Print-ISSN:
1043-4666 
TUM Einrichtung:
Neurologische Klinik und Poliklinik