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Document type:
journal article 
Author(s):
Herrmann, M; Schäfer, C; Heiss, A; Gräber, S; Kinkeldey, A; Büscher, A; Schmitt, MM; Bornemann, J; Nimmerjahn, F; Herrmann, M; Helming, L; Gordon, S; Jahnen-Dechent, W 
Title:
Clearance of fetuin-A--containing calciprotein particles is mediated by scavenger receptor-A. 
Abstract:
Fetuin-A is a liver-derived plasma protein involved in the regulation of calcified matrix metabolism. Biochemical studies showed that fetuin-A is essential for the formation of protein-mineral complexes, called calciprotein particles (CPPs). CPPs must be cleared from circulation to prevent local deposition and pathological calcification.We studied CPP clearance in mice and in cell culture to identify the tissues, cells, and receptors involved in the clearance.In mice, fetuin-A-containing CPPs we...    »
 
Journal title abbreviation:
Circ Res 
Year:
2012 
Journal volume:
111 
Journal issue:
Pages contribution:
575-84 
Language:
eng 
Print-ISSN:
0009-7330 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene