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Dokumenttyp:
journal article 
Autor(en):
Diebold, I; Petry, A; Sabrane, K; Djordjevic, T; Hess, J; Görlach, A 
Titel:
The HIF1 target gene NOX2 promotes angiogenesis through urotensin-II. 
Abstract:
Urotensin-II (U-II) has been considered as one of the most potent vasoactive peptides, although its physiological and pathophysiological role is still not finally resolved. Recent evidence suggests that it promotes angiogenic responses in endothelial cells, although the underlying signalling mechanisms are unclear. Reactive oxygen species derived from NADPH oxidases are major signalling molecules in the vasculature. Because NOX2 is functional in endothelial cells, we investigated the role of the...    »
 
Zeitschriftentitel:
J Cell Sci 
Jahr:
2012 
Band / Volume:
125 
Heft / Issue:
Pt 4 
Seitenangaben Beitrag:
956-64 
Sprache:
eng 
Print-ISSN:
0021-9533 
TUM Einrichtung:
r Kinderkardiologie und angeborene Herzfehler