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Dokumenttyp:
journal article 
Autor(en):
Schulte, EC; Mollenhauer, B; Zimprich, A; Bereznai, B; Lichtner, P; Haubenberger, D; Pirker, W; Brücke, T; Molnar, MJ; Peters, A; Gieger, C; Trenkwalder, C; Winkelmann, J 
Titel:
Variants in eukaryotic translation initiation factor 4G1 in sporadic Parkinson's disease. 
Abstract:
Recently, mutations in eukaryotic translation initiation factor 4G1 (EIF4G1) were reported as a rare cause of familial Parkinson's disease (PD). We screened the 33 exons of EIF4G1 by high-resolution melting curve analysis for variants in our Central European cohort of 376 PD cases. Variant frequency was assessed in a total of 975 PD cases and 1,014 general population controls. Eight novel nonsynonymous and four synonymous variants were identified. In our cohort, novel and previously identified n...    »
 
Zeitschriftentitel:
Neurogenetics 
Jahr:
2012 
Band / Volume:
13 
Heft / Issue:
Seitenangaben Beitrag:
281-5 
Sprache:
eng 
Print-ISSN:
1364-6745 
TUM Einrichtung:
Neurologische Klinik und Poliklinik; r Humangenetik