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Document type:
journal article 
Author(s):
Michalska, M; Machtoub, L; Manthey, HD; Bauer, E; Herold, V; Krohne, G; Lykowsky, G; Hildenbrand, M; Kampf, T; Jakob, P; Zernecke, A; Bauer, WR 
Title:
Visualization of vascular inflammation in the atherosclerotic mouse by ultrasmall superparamagnetic iron oxide vascular cell adhesion molecule-1-specific nanoparticles. 
Abstract:
Noninvasive imaging of atherosclerosis remains challenging in clinical applications. Here, we applied noninvasive molecular imaging to detect vascular cell adhesion molecule-1 in early and advanced atherosclerotic lesions of apolipoprotein E-deficient mice.Ultrasmall superparamagnetic iron oxide particles functionalized with (P03011) or without (P3007) vascular cell adhesion molecule-1-binding peptide were visualized by ultra high-field (17.6 T) magnetic resonance. Injection of P03011 resulted i...    »
 
Journal title abbreviation:
Arterioscler Thromb Vasc Biol 
Year:
2012 
Journal volume:
32 
Journal issue:
10 
Pages contribution:
2350-7 
Language:
eng 
Print-ISSN:
1079-5642 
TUM Institution:
chirurgie